SIMBRINZA – 1 BOTTLE OF 5ML

SIMBRINZA EYE DROPS contain a powerful combination of brinzolamide, a carbonic anhydrase inhibitor, and brimonidine, an alpha-2 adrenergic agonist. Brinzolamide reduces the production of aqueous humor, while brimonidine decreases its production and increases its outflow. Together, these ingredients provide a comprehensive approach to managing intraocular pressure (IOP) and controlling glaucoma. This dual-action formula helps to preserve vision and prevent damage to the optic nerve.

Usage Instructions:
Preparation: Wash your hands thoroughly before applying the eye drops.
Application: Tilt your head back slightly and pull down your lower eyelid to create a pocket.
Instillation: Place 1 drop of SIMBRINZA EYE DROPS into the pocket.
Finish: Close your eye and gently press on the inner corner of the eye to prevent the drops from draining out.
Frequency: Use as prescribed by your ophthalmologist, typically twice daily.
Medicinal Advantages:
SIMBRINZA EYE DROPS effectively manage intraocular pressure (IOP) through a dual mechanism. The combination of brinzolamide and brimonidine offers a comprehensive solution for glaucoma by both reducing aqueous humor production and enhancing its drainage. Clinical evidence supports its efficacy in controlling IOP and protecting the optic nerve from damage.

Mechanism of Action:
SIMBRINZA EYE DROPS work through two mechanisms: Brinzolamide inhibits carbonic anhydrase, reducing the production of aqueous humor, while brimonidine stimulates alpha-2 adrenergic receptors, further decreasing aqueous humor production and increasing its outflow. This dual approach results in a significant reduction in intraocular pressure (IOP).

Off-Label Uses:
While SIMBRINZA EYE DROPS are specifically indicated for glaucoma and ocular hypertension, they may also be prescribed for other conditions requiring intraocular pressure management. Consult your ophthalmologist for guidance on any off-label uses.

Expert Advice:
For optimal results, use SIMBRINZA EYE DROPS exactly as directed by your ophthalmologist. Consistent application and regular eye examinations are essential for effective management of glaucoma and monitoring of treatment progress. Do not alter the dosage without consulting your healthcare provider.

Precautions:
Avoid Contamination: Prevent contamination by not touching the tip of the dropper to any surface, including your eye.
Dosage Adherence: Follow the prescribed dosage precisely. Do not adjust the dose without consulting your ophthalmologist.
Consultation: If you experience any changes in vision or worsening symptoms, contact your ophthalmologist immediately.
Storage Conditions:
Store SIMBRINZA EYE DROPS at room temperature, away from direct light and heat. Keep the bottle tightly closed and out of reach of children. Do not freeze.

FAQs:
Q1: How often should I use SIMBRINZA EYE DROPS?
A1: Use SIMBRINZA EYE DROPS as prescribed by your ophthalmologist, typically twice daily. Adhere to your prescribed schedule for the best results.

Q2: Can SIMBRINZA EYE DROPS be used with other eye medications?
A2: Yes, but inform your ophthalmologist of any other eye medications you are using to avoid potential interactions. Follow their instructions for combining treatments.

Q3: What should I do if I miss a dose?
A3: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose—do not double up to make up for it.

Q4: Are there any additional uses for SIMBRINZA EYE DROPS?
A4: SIMBRINZA EYE DROPS are specifically indicated for glaucoma and ocular hypertension. Consult your ophthalmologist for advice on any other potential uses.

Q5: How should I store SIMBRINZA EYE DROPS?
A5: Store the eye drops in a cool, dry place, away from light. Ensure the bottle is tightly closed and avoid freezing.