ENODOM 500 MG – 10 TABLETS

ENODOM 500 MG is a combination medication designed to prevent and manage the symptoms of migraines. It contains Naproxen, an NSAID that reduces inflammation and provides pain relief, and Domperidone, a dopamine antagonist that helps alleviate nausea and vomiting, commonly associated with migraines.

By addressing both the pain and nausea aspects of migraines, ENODOM 500 MG offers comprehensive relief, making it an ideal choice for individuals who suffer from these debilitating headaches. Naproxen provides anti-inflammatory and analgesic effects by inhibiting cyclooxygenase (COX) enzymes responsible for the production of prostaglandins, which cause inflammation and pain. Domperidone works by increasing the movement of the stomach and intestines, helping to relieve nausea.

Usage Instructions:
Dosage: Take as prescribed by your healthcare provider. Typically, it is taken at the onset of a migraine or as a preventive measure.
Administration: Swallow the tablet whole with water, preferably with food to avoid stomach irritation.
Frequency: Do not exceed the recommended dose or frequency as directed by your doctor.

Medicinal Advantages:
Pain Relief & Anti-Inflammatory: Naproxen effectively reduces migraine-related pain by blocking inflammation.
Nausea Relief: Domperidone prevents the nausea and vomiting often triggered by migraines.
Dual Action: Targets both migraine pain and digestive symptoms for comprehensive treatment.

Mechanism of Action:
Naproxen (500 mg): Works by inhibiting the enzymes COX-1 and COX-2, which are involved in the production of prostaglandins that cause inflammation and pain.
Domperidone (10 mg): Blocks dopamine receptors in the gastrointestinal tract to prevent nausea and vomiting, and enhances the movement of the stomach and intestines to speed up digestion.

Off-Label Uses:
ENODOM 500 MG may also be used off-label for the treatment of other conditions that involve nausea and pain, such as menstrual cramps and general headaches.

Expert Advice:
Take with Food: To reduce the risk of stomach upset from Naproxen, it’s recommended to take ENODOM with a meal.
Avoid Excessive Use: Prolonged use of Naproxen can increase the risk of gastrointestinal problems, including ulcers or bleeding.
Nausea Management: Domperidone enhances relief from migraine-associated nausea, improving overall comfort during an episode.

Precautions:
Stomach Protection: Long-term use of NSAIDs like Naproxen can irritate the stomach lining. Consider using a gastroprotective agent if advised by your doctor.
Allergic Reactions: Inform your doctor if you have known allergies to NSAIDs or Domperidone.
Cardiovascular Risks: Naproxen may increase the risk of heart attack or stroke if used long-term or in high doses.

Storage Conditions:
Store ENODOM 500 MG in a cool, dry place away from direct sunlight. Keep it out of reach of children.

FAQs:
Q1: How quickly does ENODOM 500 MG work?
A: It typically begins to relieve migraine symptoms within 30-60 minutes, offering fast pain and nausea relief.

Q2: Can I use ENODOM 500 MG regularly for migraine prevention?
A: Yes, your doctor may prescribe it for regular use if you have frequent migraines, but it should be taken as directed to avoid side effects from long-term NSAID use.

Q3: Are there any side effects of ENODOM 500 MG?
A: Common side effects may include stomach discomfort, dizziness, dry mouth, or headache. Serious side effects include gastrointestinal bleeding, and should be reported immediately.

Q4: Can I take ENODOM 500 MG with other medications?
A: Always consult your doctor before combining ENODOM with other medications, especially blood thinners, other NSAIDs, or medications affecting stomach acid.

Q5: What should I do if I miss a dose?
A: If used for prevention, take the missed dose as soon as you remember unless it’s almost time for your next dose. Never double up on doses.