BRILLO EZ – 10 TABLET

BRILLO EZ is a powerful cholesterol-lowering medication that combines two active ingredients: Bempedoic Acid and Ezetimibe. This combination works synergistically to reduce LDL cholesterol levels, helping to prevent cardiovascular diseases such as heart attacks and strokes. Bempedoic Acid works by inhibiting cholesterol synthesis in the liver, while Ezetimibe reduces cholesterol absorption in the intestines, offering a dual mechanism for effective cholesterol management.

Key Ingredients:
Bempedoic Acid: Reduces cholesterol synthesis in the liver.
Ezetimibe: Lowers cholesterol absorption from the intestines.

Indications:
Primary Hyperlipidemia: For the treatment of high cholesterol levels, especially when LDL levels remain elevated despite statin therapy.
Atherosclerotic Cardiovascular Disease (ASCVD) Risk Reduction: For patients at risk of heart attacks and strokes due to high cholesterol.

Usage Instructions:
Dosage: The typical dose is one tablet daily. The dosage may be adjusted based on the patient’s condition and response to treatment.
Administration: Take BRILLO EZ with or without food. Swallow the tablet whole with water, without crushing or chewing.
Duration of Use: Treatment duration is based on the patient’s cholesterol levels and overall cardiovascular risk.

Medicinal Benefits:
Effective Cholesterol Reduction: Significantly lowers LDL cholesterol levels when used in combination with statins or as monotherapy in statin-intolerant patients.
Dual Mechanism: Bempedoic Acid reduces cholesterol production in the liver, while Ezetimibe decreases intestinal cholesterol absorption, providing comprehensive cholesterol control.
ASCVD Prevention: Helps reduce the risk of heart attacks, strokes, and other cardiovascular events.

Mechanism of Action:
BRILLO EZ works through a dual mechanism: Bempedoic Acid inhibits ATP citrate lyase, an enzyme involved in cholesterol synthesis, while Ezetimibe blocks the absorption of cholesterol in the small intestine. This combination effectively lowers LDL cholesterol levels in the blood, thereby reducing the risk of cardiovascular disease.

Off-Label Uses:
Familial Hypercholesterolemia: BRILLO EZ may be used in certain cases to manage cholesterol levels in patients with genetic predispositions to high cholesterol.

Expert Advice:
Liver Function Monitoring: Regular liver function tests are recommended to monitor any potential side effects on the liver.
Combination with Statins: BRILLO EZ can be used alongside statins for additional cholesterol-lowering benefits.
Dietary Considerations: Maintain a heart-healthy diet and exercise regularly to enhance the effectiveness of BRILLO EZ.

Precautions:
Pregnancy and Breastfeeding: BRILLO EZ should not be used during pregnancy or while breastfeeding. Consult your doctor for alternatives.
Liver Disease: Patients with liver disease should use BRILLO EZ with caution and under medical supervision.
Muscle Pain: Report any unexplained muscle pain, tenderness, or weakness to your healthcare provider, as it may indicate a rare side effect.
Diabetes: Monitor blood glucose levels, as Bempedoic Acid may increase blood sugar levels in some patients.
Gout: Patients with a history of gout should inform their doctor before starting BRILLO EZ, as Bempedoic Acid may increase uric acid levels.

Storage Conditions:
Temperature: Store at room temperature, between 15-30°C (59-86°F).
Packaging: Keep the tablets in their original packaging to protect from moisture and light.
Shelf Life: Do not use after the expiration date printed on the packaging.

FAQs:
Q1: How soon will I see results with BRILLO EZ?
A: LDL cholesterol levels may start to decrease within 2-4 weeks of starting BRILLO EZ. Maximum benefit is usually seen after 6-8 weeks.
Q2: Can I take BRILLO EZ with other cholesterol-lowering medications?
A: Yes, BRILLO EZ is often prescribed in combination with statins or other lipid-lowering agents for enhanced cholesterol control.
Q3: What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose.
Q4: Can BRILLO EZ cause any side effects?
A: Common side effects include muscle pain, liver enzyme elevations, and gastrointestinal symptoms. If you experience severe side effects, contact your healthcare provider.
Q5: Is it necessary to follow a specific diet while taking BRILLO EZ?
A: Following a cholesterol-lowering diet and exercising regularly will help maximize the benefits of BRILLO EZ.